1. 
Unusual weakness in one arm or leg
They are having difficulties:
Climb stairs?
How to keep an object for a long time?
Should I write a message on a shirt or button it up?
This could be one of the first engine signals.
2. 
Loss of balance and frequent falls
Coordination becomes more difficult, especially on uneven terrain.
Some describe a feeling of “weak legs” or a hesitant gait.
3. 
Muscle cramps and twitches
Fasciculations are small, involuntary muscle contractions that are visible under the skin (often in the arms or calves).
They can be frequent and bothersome.
4. 
Language difficulties
Some patients notice a weaker voice, slurred speech, or difficulty articulating correctly.
This is a typical sign when the affected area involves the facial or neck muscles.
5. 
Loss of dexterity
It is becoming increasingly difficult for you:
Write
Reach for specific objects
Typing on a keyboard
This may indicate a deterioration of the upper motor neurons.
6. 
Excessive muscle fatigue
A common sign is unusual, persistent fatigue, even after light exertion.
7. 
Swallowing difficulties
Diagnosis and treatment
There is no single test to diagnose Lou Gehrig’s disease.
The doctor relies on:
A complete neurological examination
An electromyography (EMG)
Blood tests and imaging to rule out other causes
Early detection enables a better quality of life and personalized monitoring.
Important information:
Symptom: 
What you should watch out for:
Muscle weakness in arms, legs and hands,
visible cramps/fasciculations under the skin,
speech problems, voice, articulation,
difficulty swallowing, especially upon waking,
loss of balance, unexplained falls,
warning
Charcot disease is rare and its initial symptoms can resemble other benign conditions (fatigue, stress, deficiencies, etc.).
Only a medical professional can make a reliable diagnosis.
If in doubt, consult a neurologist.
